Like V2, V4 is tuned for orientation, spatial frequency, and color. Unlike V2, V4 is tuned for object features of intermediate complexity, like simple geometric shapes, although no one has developed a full parametric description of the tuning space for V4. Visual area V4 is not tuned for complex objects such as faces, as areas in the inferotemporal cortex are.
MT sends its major output to areas located in the cortex immediately surrounding it, including areas FST, MST, and V4t (middle temporal crescent). Other projections of MT target the eye movement-related areas of the frontal and parietal lobes (frontal eye field and lateral intraparietal area).
However, in comparison with area MT, a much smaller proportion of DM cells shows selectivity for the direction of motion of visual patterns. Another notable difference with area MT is that cells in DM are attuned to low spatial frequency components of an image, and respond poorly to the motion of textured patterns such as a field of random dots. These response properties suggest that DM and MT may work in parallel, with the former analyzing self-motion relative to the environment, and the latter analyzing the motion of individual objects relative to the background.