Spello (in Antiquity: Hispellum) is an ancient town and comune (township) of Italy, in the province of Perugia in east central Umbria, on the lower southern flank of Mt. Subasio. It is 6 km (4 mi) NNW of Foligno and 10 km (6 mi) SSE of Assisi.
The old walled town lies on a regularly NW-SE sloping ridge that eventually meets the plain. From the top of the ridge, Spello commands a good view of the Umbrian plain towards Perugia; at the bottom of the ridge, the town spills out of its walls into a small modern section (or borgo) served by the rail line from Rome to Florence via Perugia.
Populated in ancient times by the Umbri, it became a Roman colony in the 1st century BC. Under the reign of Constantine the Great it was called Flavia Constans, as attested by a document preserved in the local Communal Palace.
The densely inhabited town, built with stone, retains its medieval aspect; the town is enclosed in a circuit of medieval walls built on Roman foundations, including three Roman Late Antique gates (Porta Consolare, Porta di Venere and the "Arch of Augustus") and traces of three more. The town incorporated the remains of an amphitheater.
In the plain, near San Claudio, are the remains of a semi-excavated Roman amphitheater; and a small valley to the east of the town is remarkable for its traces of Roman centuriation.
Beyond the town proper, the comune's chief monuments are the church of San Silvestro at Collepino, and the church of the Madonna della Spella with late-medieval votive frescoes and graffiti.