Manfred Mayrhofer (26 September 1926 – 31 October 2011) was an Austrian Indo-Europeanist who specialized in Indo-Iranian languages. Mayrhofer served as professor emeritus at the University of Vienna. He is noted for his etymological dictionary of Sanskrit.
Mayrhofer was born in Linz and studied Indo-European and Semitic linguistics and philosophy at the University of Graz, where he received his Ph.D. in 1949. From 1953 to 1963 he taught at the University of Würzburg, and from 1963 to 1966 he was a professor at Saarland University. In 1966 he returned to Austria, serving as professor at the University of Vienna until his retirement in 1990. He died in Vienna at the age of 85.