The rule of the Greco-Bactrians soon crumbled following these numerous wars:
"Almost at the same time that Mithridates ascended the throne among the Parthians, Eucratides began to reign among the Bactrians; both of them being great men. But the fortune of the Parthians, being the more successful, raised them, under this prince, to the highest degree of power; while the Bactrians, harassed with various wars, lost not only their dominions, but their liberty; for having suffered from contentions with the Sogdians, the Drangians, and the Indians, they were at last overcome, as if exhausted, by the weaker Parthians. Eucratides, however, carried on several wars with great spirit, and though much reduced by his losses in them, yet, when he was besieged by Demetrius king of the Indians, with a garrison of only three hundred soldiers, he repulsed, by continual sallies, a force of sixty thousand enemies. Having accordingly escaped, after a five months’ siege, he reduced India under his power. But as he was returning from the country, he was killed on his march by his son, with whom he had shared his throne, and who was so far from concealing the murder, that, as if he had killed an enemy, and not his father, he drove his chariot through his blood, and ordered his body to be cast out unburied."