Bergen and Enkheim were first mentioned as a common village in the thirteenth century. The two locations were administered together for centuries in 1936, but Bergen-Enkheim only officially became a town in 1968. In 1977 it was incorporated into the city of Frankfurt.

It is directly linked to the Rhine-Main area's RMV U-Bahn and bus network.

The Arabidopsis thaliana race Enkheim, which is important in plant molecular biology research originates here.

Every year the trade association Bergen-Enkheim organizes a trade show and the Christmas market.