In geometry, a 6-orthoplex, or 6-cross polytope, is a regular 6-polytope with 12 vertices, 60 edges, 160 triangle faces, 240 tetrahedron cells, 192 5-cell 4-faces, and 64 5-faces.

It is a part of an infinite family of polytopes, called cross-polytopes or orthoplexes. The dual polytope is the 6-hypercube, or hexeract.

This configuration matrix represents the 6-orthoplex. The rows and columns correspond to vertices, edges, faces, cells, 4-faces and 5-faces. The diagonal numbers say how many of each element occur in the whole 6-orthoplex. The nondiagonal numbers say how many of the column's element occur in or at the row's element.[1][2]

There are three Coxeter groups associated with the 6-orthoplex, one regular, dual of the hexeract with the C6 or [4,3,3,3,3] Coxeter group, and a half symmetry with two copies of 5-simplex facets, alternating, with the D6 or [33,1,1] Coxeter group. A lowest symmetry construction is based on a dual of a 6-orthotope, called a 6-fusil.

Cartesian coordinates for the vertices of a 6-orthoplex, centered at the origin are

(±1,0,0,0,0,0), (0,±1,0,0,0,0), (0,0,±1,0,0,0), (0,0,0,±1,0,0), (0,0,0,0,±1,0), (0,0,0,0,0,±1)

The 6-orthoplex can be projected down to 3-dimensions into the vertices of a regular icosahedron.[3]

It is in a dimensional series of uniform polytopes and honeycombs, expressed by Coxeter as 3k1 series. (A degenerate 4-dimensional case exists as 3-sphere tiling, a tetrahedral hosohedron.)

This polytope is one of 63 uniform 6-polytopes generated from the B6 Coxeter plane, including the regular 6-cube or 6-orthoplex.